Clinical research at FID
Clinical studies
Explore opportunities to participate in dermatology research at Florida Institute of Dermatology.
Now recruiting · Eucerin
Radiant Tone Real-World Evidence Study
A 12-week clinical research study evaluating the effectiveness and tolerability of a three-product skincare regimen in improving facial hyperpigmentation, dark spots, and uneven skin tone.
- Study duration
- 12 weeks
- Office visits
- 4 visits
- Participant compensation
- $300
Details reviewed during screening.
Opens the study screening form in Google Forms. Eligibility is confirmed during screening.
Who can participate?
General eligibility
- Women ages 18–65
- Moderate to severe facial hyperpigmentation, dark spots, or uneven skin tone
- At least one noticeable dark spot on the face
- Regular use of sunscreen with SPF 30 or higher
- Willing and able to follow the study requirements consistently
Before you apply
Important exclusions
- Use of spironolactone, tretinoin, or prescription skin-lightening products (such as hydroquinone) within the past 3 months
- Pregnancy, breastfeeding, or plans to become pregnant during the study
- Certain recent facial cosmetic procedures or surgeries
- History of skin cancer
These are general criteria, not the full eligibility requirements. Additional requirements will be reviewed during screening.
Your study schedule
Four visits. Twelve weeks.
Visit 1
Baseline
Visit 2
Week 4
Visit 3
Week 8
Visit 4
Week 12
Taking part
What participation involves
- Use the provided skincare products every day throughout the study.
- Complete a daily diary confirming product use.
- Maintain your existing skincare and makeup routines without introducing new products, except for the products provided as part of the study.
- Continue using your regular sunscreen.
- Attend all scheduled study visits.
- Have facial photographs taken to document changes throughout the study.
We are looking for dependable participants who can follow the instructions consistently and attend every required appointment.

Study questions
Before you take part
What is this study evaluating?
The effectiveness and tolerability of a three-product skincare regimen in improving facial hyperpigmentation, dark spots, and uneven skin tone. Research participation does not guarantee improvement.
Will I receive compensation?
Participants receive $300 in compensation for participation. Specific compensation details will be reviewed during the screening process.
How many office visits are required?
Four visits over 12 weeks: Baseline, Week 4, Week 8, and Week 12. Participants must be able to consistently follow the study instructions and attend all required appointments.
Can I participate if I use prescription skincare?
Use of spironolactone, tretinoin, or prescription skin-lightening products such as hydroquinone within the past 3 months is an exclusion. Do not stop or change prescribed treatment to qualify; discuss your medications with the study team during screening.
Does submitting the form mean I am enrolled?
No. The form is the first step toward screening. The study team will review the full eligibility requirements before participation is confirmed.
Radiant Tone study
Interested in participating?
Complete the study screening form to begin the eligibility review process.
